Mesotrione is a herbicide that has been on the market for over 15 years and is commonly used on maize crops ¹. It is an HPPD inhibitor that can inhibit the activity of hydroxypyruvate dioxygenase (HPPD) and ultimately affect the generation of carotenoids ². Mesotrione can effectively prevent weeds such as abutilon, cockle, and amaranth from growing in corn fields ².

A comprehensive review of available scientific literature reveals that mesotrione applied as recommended ensures the desired effects on sensitive crops while exhibiting a favorable toxicological and environmental profile. According to studies conducted so far, mesotrione presents no significant risks to humans and other non-target organisms or to the environment. Its degradation by soil microorganisms is fast, ensuring a low possibility of retrieving mesotrione in groundwater. Its terminal residues in soil, maize grain, and maize straw are below the limit of quantification ¹.

Here are some articles that you might find interesting:

1. “Mesotrione Herbicide: Efficiency, Effects, and Fate in the Environment after 15 Years of Agricultural Use” by Louis Carles et al¹
2. “Mesotrione-induced oxidative stress and DNA damage in earthworms” ²
3. “Efficacy of mesotrione used at reduced doses for post-emergence weed control in maize” ³
4. “Mesotrione: a new preemergence herbicide option for wild radish” ⁴

Would you like more information on a specific aspect of mesotrione?

Timing is important (pre bud break)
Should be applied at the lowest concentration indicated.

https://smallfruits.org/files/2020/12/2021-Caneberry-Spray-Guide.pdf
PREEMERGENCE Broadleaf weeds mesotrione (Callisto) 3 to 6 fl oz Plantings established 1 year or more. 12 Apply pre-bloom as a directed spray in raspberry or blackberry. Callisto has PRE and POST activity. Callisto may be applied at a rate up to 6 fl oz/A. Sequential applications of 3 fl oz/A may be applied so long there is at least 14 days or more between applications. The addition of COC at 1% v/v (1 gal per 100 gal of spray solution) is necessary for POST weed control. Care must be taken to make sure the adjuvant is not one that may injure caneberry leaves. MOA 27.

COC=adjuvant surfactant

I ran elements of the article through my AI search generator.
Another Study using Granular Casoron for weed control

Response from MSFT

First generated response from Google's AI... Googles AI generated 3d responses from the get go.
Another Brand of Mesotrione

Red raspberries are moderately tolerant to mesotrione, a broad-spectrum herbicide that is used to control a variety of broadleaf weeds. However, if applied too heavily or too late in the season, mesotrione can damage red raspberries.

The best time to apply mesotrione to red raspberries is in the spring, before the plants have begun to grow. A directed application, meaning that the herbicide is applied directly to the weeds and not to the raspberries, is recommended. If you must apply mesotrione after the raspberries have begun to grow, be sure to use the lowest possible rate and apply it only to the weeds.

If you notice any signs of damage to your red raspberries after applying mesotrione, such as yellowing or wilting leaves, contact your local extension office for assistance.

Here are some additional tips for using mesotrione safely on red raspberries:

• Read and follow the label directions carefully.
• Apply mesotrione only in the spring, before the raspberries have begun to grow.
• Use the lowest possible rate of application.
• Apply mesotrione only to the weeds, not to the raspberries.
• Monitor your raspberries for signs of damage after applying mesotrione.
• If you notice any damage, contact your local extension office for assistance.

Second Generated Response...

Red raspberries are moderately tolerant to mesotrione, a herbicide that is used to control broadleaf weeds in a variety of crops. However, if mesotrione is applied too heavily or too late in the season, it can damage red raspberries.

In one study, red raspberries were treated with mesotrione at rates of 0.25, 0.5, 1.0, and 2.0 pounds per acre. The results showed that the plants were most tolerant to mesotrione when it was applied at the lowest rate (0.25 pounds per acre). At the higher rates, the plants showed signs of damage, including chlorosis (yellowing of the leaves) and necrosis (death of tissue).

The study also found that the timing of application was important. When mesotrione was applied before bud break, the plants were more tolerant than when it was applied after bud break. This is because the plants are more susceptible to damage when they are actively growing.

Overall, the study showed that red raspberries are moderately tolerant to mesotrione. However, it is important to use the herbicide according to the label directions to avoid damaging the plants.

Here are some tips for using mesotrione safely on red raspberries:

• Apply the herbicide according to the label directions.
• Do not apply the herbicide too heavily.
• Apply the herbicide before bud break.
• Monitor the plants for signs of damage and take action if necessary.

Third response

Red raspberry is relatively tolerant to mesotrione, but it is important to follow the label directions carefully to avoid injury to the plants. Mesotrione is a post-emergent herbicide that is used to control broadleaf weeds in a variety of crops, including raspberries. It works by inhibiting the growth of new cells, which eventually leads to the death of the weed.

Red raspberry is considered to be moderately tolerant to mesotrione, meaning that it can withstand a certain amount of exposure to the herbicide without suffering significant injury. However, if the herbicide is applied at too high of a rate or if it is applied to young, susceptible plants, it can cause damage to the raspberry plants.

The most common symptoms of mesotrione injury in red raspberry are chlorosis (yellowing of the leaves) and necrosis (death of the leaves). In severe cases, the entire plant may die. If you suspect that your raspberry plants have been injured by mesotrione, it is important to take action immediately to prevent further damage.

The first step is to stop using the herbicide. If the herbicide has already been applied, you can try to wash it off of the plants with water. However, this is only effective if the herbicide has not had time to dry on the leaves.

If the plants have already begun to show signs of injury, you can try to treat them with a foliar fertilizer. This will help to encourage new growth and help the plants to recover.

In severe cases, you may need to remove the affected plants and replant them. Be sure to choose a herbicide-tolerant variety of raspberry to avoid future problems.

To prevent injury to your raspberry plants, it is important to follow the label directions carefully when using mesotrione. Be sure to apply the herbicide at the correct rate and to avoid spraying the plants when they are wet. You should also avoid applying the herbicide to young, susceptible plants.

Mesotrione is a herbicide that is used to control broadleaf weeds in a variety of crops, including blueberries. However, it can also cause damage to raspberries. The symptoms of mesotrione damage to raspberries include:

• Chlorosis (yellowing of the leaves)
• Necrosis (death of the leaves)
• Stunted growth
• Reduced fruit yield

The severity of the damage will depend on the rate of application, the timing of application, and the variety of raspberry. In some cases, the damage can be so severe that the raspberry plant will die.

If you suspect that your raspberries have been damaged by mesotrione, the best course of action is to contact your local extension office or a certified arborist for diagnosis and treatment recommendations.

Here are some tips to help prevent mesotrione damage to raspberries:

• Read the label carefully and follow the directions.
• Apply the herbicide only when the raspberries are dormant.
• Do not apply the herbicide to wet foliage.
• Use a lower rate of application than recommended for blueberries.
• Monitor the raspberries for signs of damage and apply a foliar spray of a chelated iron supplement if necessary.